Advance OR Primitif? Reseach or Ecological Survey? Can it fulfill High Impact Factor Journals>

Amazing blood-clotting design in ‘primitive’ creature used in space research!

The horseshoe crab (a living fossil) has many design features that not only help the crab itself, but are also useful for mankind. Horseshoe crab Limulus polyphemus, used to develop a test for bacteria. Bacterial cell walls contain distinctive LPS molecules (lipopolysaccharides, molecules containing sugar units and a fat). These trigger a cascade of enzyme reactions in horseshoe crab blood that attack the bacterial proteins and culminate in the production of a protein called fibrin. This clots the crab’s blood and, in the wild, would effectively seal a wound.
Fifty years ago, the MBL biologists exploited these coagulation properties to develop a test for microbial toxins and impurities on instruments used by pharmaceutical companies. This is called the Limulus Amebocyte Lysate test (LAL).

‘Horseshoe crab blood cells act like a primitive immune system’

if it is so ‘primitive’, then why has it survived for the alleged millions of years


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1.Simple biology research on breeding/ecology of horseshoe crab attracts NASA.
2.long time of research activities with big grants.
3.understanding basic research; biology, ecology of wild animals
4.America understand biology, ecology (including ecological survey), behaviour, habitat, blood, physiology and conservation (including public awareness)
5.Research found horshoe crabs good for human health.
6.We Asian take a short cut journey hunt and eat the animals.
7.Asian do research on cooking and ingridient to improve thev taste of cooking.
8.Even top management does not value basic sciences (they prbably listen to chef rather than scientists)
9.We only see, think and interpret what is in front of our eyes. Something behind our ears we cannot feel, see, think, evaluate and use them.
10.how we are going to think about advance research and beyond ordinary people thinking? Do we need to wait until artist (singer and jokers) and politician to advice our scientists?